This article reviews epidemiology of malignant hepatobiliary tumor and its feature of gene mutation to recognize the rule about familial inheritance of this two diseases. 对肝胆恶性肿瘤的流行病学及基因突变特点进行综述,了解这两种疾病的家族遗传规律。
As with familial adenomatous polyposis, the inheritance pattern is autosomal dominant. 家族性腺瘤息肉病的遗传方式是常染色体显性遗传。
Objective: To explore the familial inheritance tendency of obsessive-compulsive disorder ( OCD) and the role of biotic and social culture factor influence for the generation of the disorder. 目的:探讨强迫症的家族遗传倾向及生物和文化因素对其发病的作用。
Methods Using familial analysis, tests for multifactorial inheritance and segregation analysis, we studied 210 pedigrees with IEP found in a population survey in Shangdong province. 方法采用家系分析、多基因分析和分离分析的方法,对山东省遗传病群体调查中发现的210个IEP家系进行了研究。
The incidence rate within the 72 families pedigree with familial bronchial asthma, including 109 core pedigrees, is 0.46. Analysis shows a tendency towards single gene inheritance. 72个家族性支气管哮喘的家系,包括109个核心家系,其亲属的患病率为0.46。分析结果表明,有单基因遗传的倾向。
Conclusion Genetic factors play a major role in the pathogenesis of familial gallstone disease, characterized by autosomal dominant inheritance. 结论(1)家族性胆囊结石病具有常染色体显性遗传特点,遗传因素是发病的基础。
In this article 3 cases of neurofibromatosis with three generation familial inheritance are reported. 本文通过3例具有3代家族关系发病史的神经纤维瘤病,进一步证明本病属常染色体显性遗传。
Unified questionnaire has been used to collect environmental factors which include society demography information, lifestyle, eating habit, major drinking water, history of the development of liver cancer correlated disease and familial inheritance, and so on. 制定统一的调查表,调查表内容具体包括社会人口学资料、生活方式、饮食习惯、主要饮用水源、肝癌相关疾病发生史、家族遗传史等。